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Interpreting NT-proBNP and BNP in Clinical Decision-Making

…patients with impaired renal function, reflecting both reduced clearance and the high prevalence of structural heart disease in this population. Obesity is associated with lower…

High-Sensitivity Troponin: 0/1-Hour Rule-In and Rule-Out Algorithms

…and Pathophysiological Basis High sensitivity cardiac troponin (hs cTn) assays detect circulating troponin released from injured cardiomyocytes at substantially lower concentrations than earlier generation assays…

ACE Inhibitors: Initiation, Titration and Creatinine Monitoring

…Higher doses are more effective than lower doses in preventing hospitalization. Abrupt withdrawal of treatment with an ACE inhibitor may lead to clinical deterioration and…

Blood gas interpretation: quick reference for acid-base disorders

…and supplemental oxygen [1]. Distinguish between: Acidaemia and alkalaemia , which describe the current pH of the blood. Acidosis and alkalosis , which describe processes that lower…

Dietary Patterns and Cardiovascular Outcomes

…with lower consumption of meat, processed meat, butter and cream. Primary cardiovascular events occurred in 8 of 302 participants in the Mediterranean group compared with…

Common laboratory tests

…on HbA1c. Albumin affects the total calcium — use the ionised calcium or correct for albumin. Biotin supplements interfere with many immunoassays, including troponin and TSH.

Warfarin therapy

…blood count, creatinine with eGFR and liver function tests before starting. A complete medication list including over the counter drugs, herbal remedies and supplements. An…

Amiodarone: Loading, Maintenance Dosing and Monitoring Schedule

…and incompletely absorbed after oral administration, with systemic bioavailability ranging from 25% to 65% and minimal hepatic first pass extraction. Following a single oral dose…

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