Articles & courses

Articles
High-Sensitivity Troponin: 0/1-Hour Rule-In and Rule-Out Algorithms

…approximately 20–50%. Their greater analytical sensitivity improves diagnostic accuracy and negative predictive value in patients with suspected acute coronary syndrome (ACS). Cardiac troponin is…

Amiodarone: Loading, Maintenance Dosing and Monitoring Schedule

…days, and often 1 to 3 weeks or occasionally longer; loading doses mitigate this delay. During chronic therapy, plasma concentrations correlate well with oral doses…

Dietary Patterns and Cardiovascular Outcomes

…reduction in major cardiovascular events with a Mediterranean diet supplemented with either nuts or extra virgin olive oil compared with a low fat dietary pattern…

Interpreting NT-proBNP and BNP in Clinical Decision-Making

…more closely related to the clinical state during treatment with an angiotensin receptor–neprilysin inhibitor. Clinical Applications Natriuretic peptides have three principal roles: Supporting or…

Common laboratory tests

…based on HbA1c. Albumin affects the total calcium — use the ionised calcium or correct for albumin. Biotin supplements interfere with many immunoassays, including troponin and…

Warfarin therapy

…what happens when the INR runs away or the patient bleeds. In Sweden the treatment is usually managed from an anticoagulation clinic with dosing support…

ACE Inhibitors: Initiation, Titration and Creatinine Monitoring

…ACE inhibitors, especially in patients with preexisting azotemia, hypotension, hyponatremia, diabetes mellitus, or in those taking potassium supplements. When managing albuminuria or CKD, the serum…

Blood gas interpretation: quick reference for acid-base disorders

…supplemental oxygen, sampling technique, air bubbles and analytical delay, and compare with the electrolyte panel Rapid classification pH pCO₂ HCO₃ Likely dominant process : : : : Low High…

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