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Warfarin therapy

…and supplements. An assessment of bleeding risk and the risk of falls; anaemia and a known gastrointestinal source are investigated before starting. A referral or…

ACE Inhibitors: Initiation, Titration and Creatinine Monitoring

…ACE inhibitors, especially in patients with preexisting azotemia, hypotension, hyponatremia, diabetes mellitus, or in those taking potassium supplements. When managing albuminuria or CKD, the serum…

Interpreting NT-proBNP and BNP in Clinical Decision-Making

…more closely related to the clinical state during treatment with an angiotensin receptor–neprilysin inhibitor. Clinical Applications Natriuretic peptides have three principal roles: Supporting or…

Common laboratory tests

…based on HbA1c. Albumin affects the total calcium — use the ionised calcium or correct for albumin. Biotin supplements interfere with many immunoassays, including troponin and…

Blood gas interpretation: quick reference for acid-base disorders

…metabolic alkalosis. A high pH with a low pCO₂ suggests respiratory alkalosis 3 Is the compensation adequate? Calculate the expected pCO₂ or HCO₃. A value…

Amiodarone: Loading, Maintenance Dosing and Monitoring Schedule

…or ventricular fibrillation (VF). IV infusions can be safely continued for 2 to 3 weeks. IV amiodarone is generally well tolerated, even in patients with…

High-Sensitivity Troponin: 0/1-Hour Rule-In and Rule-Out Algorithms

…that supplements the initial concentration and can approximate the information obtained from longer serial intervals. Clinical Presentation and Initial Clinical Context Chest pain or discomfort…

Dietary Patterns and Cardiovascular Outcomes

…reduction in major cardiovascular events with a Mediterranean diet supplemented with either nuts or extra virgin olive oil compared with a low fat dietary pattern…

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