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Dual Antiplatelet Therapy Duration After Acute Coronary Syndromes and Elective Percutaneous Coronary Intervention

…reduce coronary thrombotic events without exposing the patient to disproportionate bleeding risk. Shortening treatment may reduce bleeding but can increase myocardial infarction or stent thrombosis…

Drug-Eluting Coronary Stents: Evolution, Evidence and Stent Choice

…stents (BMS) in response to restenosis caused principally by neointimal hyperplasia. Contemporary DES combine a metallic scaffold, a polymeric or polymer free drug delivery system…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…ACS population. Clinical context and patient selection Acute coronary syndrome ACS includes ST segment elevation myocardial infarction (STEMI), non ST elevation myocardial infarction (NSTEMI), and…

Antiplatelet Therapy in Secondary Prevention After Myocardial Infarction

…central component because platelet activation and aggregation contribute importantly to arterial thrombus formation, recurrent coronary occlusion, and stent thrombosis. Aspirin inhibits the cyclooxygenase 1 pathway…

Fourth Universal Definition of Myocardial Infarction: Types 1–5

…4a MI: Represents a periprocedural myocardial infarction associated with percutaneous coronary intervention (PCI). Type 4b MI: Denotes myocardial infarction related to stent thrombosis following PCI…

The Fourth Universal Definition of Myocardial Infarction: Types 1–5

…myocardial injury may occur without myocardial ischaemia. Non ischaemic myocardial injury may accompany numerous cardiac and systemic disorders, including: Cardiac causes Systemic causes Heart failure…

Stent Thrombosis: Timing, Causes, Diagnosis, and Prevention

…fulfilled. The temporal relationship to stent implantation should always be specified. Coronary arterial thrombi are predominantly platelet rich because they form under high shear conditions…

In-Stent Restenosis: Mechanisms and Treatment

…percutaneous coronary intervention (PCI). In contemporary practice, ISR remains the most frequent cause of PCI failure, despite its substantially lower incidence with drug eluting stents…

Periprocedural Myocardial Infarction After PCI and CABG

…Periprocedural myocardial infarction (MI) is myocardial necrosis temporally related to coronary revascularization. It may follow percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG)…

Intravascular Imaging: IVUS and OCT for PCI Optimisation

…thrombus, and implanted stents. The principal modalities used in the catheterization laboratory are intravascular ultrasound (IVUS) and optical coherence tomography (OCT). Unlike coronary angiography, which…

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