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🟠 Inotropes and Vasopressors

…cardiac contractile force (contractility). Several endogenous and synthetic agents exist and are frequently combined to achieve the desired hemodynamic outcome. Most agents exhibit both vasopressor…

Sotalol: Initiation, QT Monitoring and Renal Dosing

…proarrhythmia, and severe bradycardia. Patients should be monitored for arrhythmias and QT prolongation with each dose adjustment, typically waiting 2 to 3 days to attain…

Inotropes and Vasopressors: Doses, indications, contraindications and effects

…cardiac contractile force (contractility). Several endogenous and synthetic agents exist and are frequently combined to achieve the desired hemodynamic outcome. Most agents exhibit both vasopressor…

🟠 Aspirin (Acetylsalicylic acid)

…severe kidney disease (glomerular filtration rate < 30 mL/min). Patients with mild to moderate heart failure, kidney or liver disease, especially when combined with…

Short Synacthen test

…Marked atopic disease, particularly severe asthma and a history of anaphylaxis — a relative contraindication; the test is then performed with preparedness for anaphylaxis. An untreated…

Contrast-Associated Acute Kidney Injury: Risk Assessment and Prevention

…with a peak at approximately 3–5 days and resolution within about 1 week in the usual course. Severe AKI requiring dialysis is uncommon except…

Ivabradine: Indications, Dosing and Heart-Rate Targets

…evidence for their efficacy is limited. Ivabradine alone or combined with a beta blocker should be considered in symptomatic patients. This is a class IIa…

ST-Elevation Myocardial Infarction: Diagnosis and Electrocardiographic Criteria

…usually subside with cessation of activity, distinguishing it from angina pectoris. The location of the pain beneath the xiphoid and epigastrium, combined with patient denial…

Statin Intolerance and Statin-Associated Muscle Symptoms

…ciclosporin, warfarin and grapefruit juice. Gemfibrozil should not be combined with statins because it alters statin absorption, hepatic uptake and disposition. Clinical presentation and symptoms…

Type 2 Diabetes and Cardiovascular Risk Management

…combined effects of hyperglycaemia, hypertension, dyslipidaemia, obesity, smoking and other conventional risk factors, together with diabetes specific vascular and metabolic abnormalities. Diabetes is associated with…

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