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Secondary Hypertension: When and How to Investigate

… rather, it is an indicator of increased cardiovascular risk and a setting in which secondary hypertension is relatively common. Patients presumed to have resistant hypertension…

Antiplatelet Therapy in Secondary Prevention After Myocardial Infarction

…absence of contraindications, using a loading dose followed by maintenance treatment. The source material does not specify the loading dose. Efficacy and harms In secondary…

🟠 Aspirin (Acetylsalicylic acid)

…first sign of skin rash, mucosal lesions, or hypersensitivity. Interactions Pharmacodynamic interactions Anticoagulants, thrombolytics, or other platelet aggregation inhibitors: Salicylates inhibit platelet function and enhance…

Cardiac Rehabilitation After Myocardial Infarction

…and mortality The modern concept of rehabilitation has evolved from early post infarction physical activity programmes into a structured centre of secondary cardiovascular prevention in…

Aspirin in Primary Prevention: Current Recommendations

…pathway of platelet activation, its antiplatelet effect is relatively limited compared with agents that inhibit other platelet pathways. The distinction between primary and secondary prevention…

Left Bundle Branch Block: ECG criteria and clinical implications

…widened QRS complex and secondary ST T wave abnormalities [7]. Diagnostic Criteria The diagnostic requirements for LBBB vary by the stringency of the criteria applied…

Lipid-Lowering Therapy: Statins as First-Line Treatment

…and acute coronary syndromes (ACS). Its principal therapeutic objective is reduction of low density lipoprotein cholesterol (LDL C), the primary lipid target in contemporary secondary…

Primary Aldosteronism: Screening and Management

…of secondary hypertension. Aldosterone acts principally through the mineralocorticoid receptor (MR). After entering target cells, it binds the MR, which translocates to the nucleus and…

Resistant Hypertension: Evaluation and Treatment

…kidney function; Excess dietary sodium and volume overload; Concomitant drugs or conditions that increase blood pressure; or An undiagnosed secondary cause of hypertension. White coat…

Risk Factor Modification: The Evidence Base for Primary Prevention

…principal scope of primary prevention, secondary prevention provides an important contrast. Patients with manifest clinical disease are at high risk of progression and generally require…

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