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Heart Failure With Preserved Ejection Fraction: Diagnosis and Treatment

… progressive ventricular remodeling may also occur in primary valvular disease. Increasing severity of mitral regurgitation is associated with worse outcomes. Pulmonary hypertension secondary to left…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…males and approximately 10 years later in females. Untreated HoFH is associated with extensive premature and progressive ASCVD; CAD and aortic stenosis may occur before…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…classic claudication. Asymptomatic or atypical PAD remains clinically important. Reduced activity may lead to progressive functional decline, sedentary behaviour and loss of independence. Identification of…

Antiplatelet Therapy in Secondary Prevention After Myocardial Infarction

…pathophysiological basis Secondary prevention after myocardial infarction (MI) encompasses long term interventions intended to reduce recurrent infarction, ischaemic stroke, cardiovascular death, and progression of atherosclerotic…

Cardiac Rehabilitation After Myocardial Infarction

…and infarction Definition and Purpose Cardiac rehabilitation is a comprehensive, multidisciplinary secondary prevention intervention for patients with cardiovascular disease, including those recovering from myocardial infarction…

Hypertriglyceridaemia: Management and Cardiovascular Risk

…relationship between triglyceride concentrations and aortic disease is less clearly defined, although triglycerides may contribute to the development and progression of aortic pathology. Severe HTG…

Left Bundle Branch Block: ECG criteria and clinical implications

…recovery patterns within the left ventricle, resulting in a widened QRS complex and secondary ST T wave abnormalities [7]. Diagnostic Criteria The diagnostic requirements for…

Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Multivessel Coronary Artery Disease

…secondary prevention. PCI treats focal stenotic segments, whereas CABG provides a bypass beyond diseased segments. The latter may also protect against future proximal disease progression…

Risk Factor Modification: The Evidence Base for Primary Prevention

…secondary prevention provides an important contrast. Patients with manifest clinical disease are at high risk of progression and generally require all appropriate evidence based measures…

Smoking Cessation: Pharmacotherapy and Cardiovascular Benefit

…cessation is therefore the preferred therapeutic endpoint. The cardiovascular benefits of cessation extend across primary and secondary prevention. Observational evidence indicates that cessation lowers the…

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