Cardiology Endocrinology & metabolism Definition and pathophysiology Secondary hypertension is elevated blood pressure attributable to a specific, identifiable underlying cause. It should be considered in every…

…does not specify the loading dose. Efficacy and harms In secondary prevention trials involving patients with previous vascular disease, aspirin reduced the combined incidence of…

…Unstable coronary artery disease. Stable angina pectoris. Secondary prophylaxis to prevent recurrence of cerebrovascular diseases, such as: Transient ischemic attacks (TIA). Stroke Contraindications Cross reactivity…

…left ventricular function The amount of residual viable myocardium exposed to ischaemic risk Susceptibility to serious ventricular arrhythmias Cardiac rehabilitation addresses these determinants indirectly and…

…other platelet pathways. The distinction between primary and secondary prevention is fundamental: Primary prevention refers to individuals without established atherosclerotic cardiovascular disease (ASCVD), coronary artery…

…a significant reorganization of the activation and recovery patterns within the left ventricle, resulting in a widened QRS complex and secondary ST T wave abnormalities …

…and acute coronary syndromes (ACS). Its principal therapeutic objective is reduction of low density lipoprotein cholesterol (LDL C), the primary lipid target in contemporary secondary…

…of secondary hypertension. Aldosterone acts principally through the mineralocorticoid receptor (MR). After entering target cells, it binds the MR, which translocates to the nucleus and…

… Increased mortality; and A higher probability of secondary hypertension. Patients may also have comorbid features associated with a greater cardiovascular risk among those with resistant…

…secondary prevention provides an important contrast. Patients with manifest clinical disease are at high risk of progression and generally require all appropriate evidence based measures…