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Drug-Eluting Coronary Stents: Evolution, Evidence and Stent Choice

…to restenosis caused principally by neointimal hyperplasia. Contemporary DES combine a metallic scaffold, a polymeric or polymer free drug delivery system, and an antiproliferative agent…

In-Stent Restenosis: Mechanisms and Treatment

…percutaneous coronary intervention (PCI). In contemporary practice, ISR remains the most frequent cause of PCI failure, despite its substantially lower incidence with drug eluting stents…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

…and thrombosis interact to produce focal arterial lesions. Although epicardial coronary arteries are a major site of disease, atherosclerosis is systemic and may affect multiple…

The Fourth Universal Definition of Myocardial Infarction: Types 1–5

…percutaneous coronary intervention (PCI) Type 4b MI caused by stent or scaffold thrombosis Type 4c MI caused by restenosis Type 5 MI associated with coronary…

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