…of function mutations in KCNQ1 (LQT1) and KCNH2 (LQT2), and gain of function mutations in SCN5A (LQT3). These genetic anomalies disrupt the cardiac ion channels…

…of function mutations in KCNQ1 (LQT1) and KCNH2 (LQT2), and gain of function mutations in SCN5A (LQT3). These genetic anomalies disrupt the cardiac ion channels…

…was SCN5A , the gene encoding the alpha subunit of the cardiac voltage gated sodium channel (Nav1.5) [6] . Loss of function (LOF) mutations in SCN5A…