11 träffar

DrugCalcium salt for intravenous membrane stabilisation and calcium supplementation
Calcium gluconate

…Braun Calcium salt for intravenous membrane stabilisation and calcium supplementation First-line intervention in hyperkalaemia with ECG changes: calcium restores the margin between resting membrane…

DrugNon-selective COX inhibitor with COX-2 predominance, phenylacetic acid derivative
Diclofenac

…good effect in musculoskeletal and postoperative pain, but with the most unfavourable cardiovascular profile in the class — the increase in risk for myocardial infarction, stroke…

DrugNon-selective COX inhibitor, propionic acid derivative
Ibuprofen

…COX inhibitor, propionic acid derivative The first-line NSAID in Sweden and the one with the least cardiovascular risk at a low dose. A short…

DrugElectrolyte concentrate for potassium replacement
Potassium chloride

…Braun Kaleorid Electrolyte concentrate for potassium replacement Potassium deficiency is corrected slowly because extracellular potassium is only two per cent of the body's total…

DrugThiazide diuretic
Bendroflumethiazide

…curve for blood pressure flattens already at 2,5 mg, while the adverse effect curves for potassium, sodium, urate, and glucose continue to rise — higher…

DrugLong-acting benzodiazepine with active metabolite
Diazepam

…the active metabolite desmethyldiazepam up to four, so the concentration continues to rise for a week after initiation. That long tail is simultaneously the point…

DrugDirect factor Xa inhibitor
Apixaban

…dosing and no routine monitoring. Lower risk of intracranial haemorrhage than warfarin — but the short half-life means a missed dose has consequences within hours.

DrugLong-acting basal insulin
Insulin glargine

…meals and overnight, with a largely flat profile over 24 hours and therefore a lower risk of nocturnal hypoglycaemia than NPH insulin. It is titrated…

DrugIndirect thrombin and factor Xa inhibitor via antithrombin
Heparin (unfractionated)

…short notice. The disadvantages are continuous infusion, an unpredictable dose–response relationship due to binding to plasma proteins, and the risk of heparin-induced thrombocytopenia.

DrugSelective If-channel inhibitor in the sinus node
Ivabradine

…symptomatic patient with HFrEF who remains above 70 beats per minute despite maximally tolerated beta-blockade, where SHIFT demonstrated reduced risk of heart failure hospitalisation.

DrugUltra-short-acting β₁-selective blocker
Esmolol

…20–30 minutes after the infusion ends, it is useful in patients where beta-blockade is desirable but risky — impending heart failure, obstructive lung disease…