…macrophage infiltration, smooth muscle cell proliferation, and extracellular matrix deposition, ultimately leading to the formation of atherosclerotic plaques [1] . While stable plaques are characterized by…
…as limb complications. Atherosclerotic lesions generally affect large and medium sized arteries. Pathological features include plaque formation with calcium deposition, medial thinning, destruction of muscular…
…disease (ASCVD). Atherosclerosis develops through the progressive deposition and retention of LDL C and other apoB containing lipoproteins within the arterial wall. This initiates inflammatory…
…Doppler), which is explained by the fact that the pulse repetition frequency (PRF) is reduced when obtaining both a 2D image and Doppler signals simultaneously…
…the former. This allows much higher velocitites to be measured. Continuous wave Doppler is therefore not limited by pulse repetition frequency (PRF). Figure 1. The…
…has become increasingly clear in the past few decades that atherosclerosis is not caused by the passive deposition of lipids into the coronary artery walls…
…Cardiac Amyloidosis Definition and Pathophysiology Cardiac amyloidosis (CA) is a protein misfolding disorder characterized by the extracellular deposition of misfolded fibrillar proteins in the myocardium…
…receptor endocytosis and produce an FH like phenotype. Individuals with a single pathogenic variant have heterozygous FH (HeFH). Biallelic pathogenic variants cause homozygous FH (HoFH…
…no rotation. This example illustrates the significance of high pulse repetition frequency in order to obtain accurate assessments of blood flow and myocardial movement. Figur…
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