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Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…cardiovascular disease (ASCVD), particularly coronary artery disease (CAD). FH results from pathogenic variants affecting proteins in the hepatic LDL receptor pathway. Reduced cellular uptake and…

Cardiac amyloidosis

…present with symptoms of predominant right heart failure, including lower extremity edema, ascites, and hepatic enlargement [8, 10]. Atrial arrhythmias, particularly atrial fibrillation and flutter…

ApoB and Non-HDL Cholesterol in Cardiovascular Risk Assessment

…disease (ASCVD). Atherosclerosis develops through the progressive deposition and retention of LDL C and other apoB containing lipoproteins within the arterial wall. This initiates inflammatory…

Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

…macrophage infiltration, smooth muscle cell proliferation, and extracellular matrix deposition, ultimately leading to the formation of atherosclerotic plaques [1] . While stable plaques are characterized by…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

Cardiology Clinical medicine Definition and pathophysiology Peripheral artery disease (PAD) is a clinical disorder caused by stenosis or occlusion of the aorta or arteries supplying…

Color Doppler

…Doppler), which is explained by the fact that the pulse repetition frequency (PRF) is reduced when obtaining both a 2D image and Doppler signals simultaneously…

Continuous Wave Doppler (CW Doppler)

…the former. This allows much higher velocitites to be measured. Continuous wave Doppler is therefore not limited by pulse repetition frequency (PRF). Figure 1. The…

Introduction to Coronary Artery Disease (Ischemic Heart Disease)

…plays a key role. As the inflammation and deposition of lipids progress, an atherosclerotic plaque forms in the wall of the artery. Such atherosclerotic plaques…

Pulsed Wave Doppler

…no rotation. This example illustrates the significance of high pulse repetition frequency in order to obtain accurate assessments of blood flow and myocardial movement. Figur…

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