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Diuretic Strategy and Decongestion in Heart Failure

…formally to reduce heart failure mortality; its established role is symptom relief and prevention of recurrent congestion and hospitalization. Clinical presentation and symptoms Symptoms of…

Atropine: Dosing in Bradycardia and Its Limitations

…level, producing atrioventricular (AV) or intraventricular blocks. Isolated sinus bradycardia in the early hours following infarction may be associated with hemodynamic compromise. More broadly, bradyarrhythmic…

Posterior Myocardial Infarction: Diagnosis on the Standard ECG

…Consequently, posterior infarction should not be regarded as an isolated electrocardiographic pattern in every case; it may represent the posterior component of a broader infarct…

No-Reflow Phenomenon During Percutaneous Coronary Intervention: Prevention and Treatment

…Possible manifestations include: Persistent or recurrent myocardial ischemia Deterioration in ventricular function Hemodynamic instability Periprocedural myocardial infarction Cardiogenic shock Cardiac arrest The severity may be…

In-Stent Restenosis: Mechanisms and Treatment

Myocardial ischemia and infarction Definition and Clinical Significance In stent restenosis (ISR) is recurrent narrowing within a previously implanted coronary stent. It represents a form…

Antiplatelet Therapy in Secondary Prevention After Myocardial Infarction

Myocardial ischemia and infarction Pharmacology & dosing Definition and pathophysiological basis Secondary prevention after myocardial infarction (MI) encompasses long term interventions intended to reduce recurrent infarction…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…or severity; angina that awakens the patient from sleep. Patients receiving modified antiplatelet therapy require clinical surveillance for both recurrent ischemia and bleeding. The source…

Ischemic Cardiomyopathy: Myocardial Viability Assessment and Revascularization

…Heart failure (HF) symptoms may result from several overlapping processes: Recurrent or extensive MI with necrosis and scar formation Diffuse myocardial fibrosis Reversible ischemic dysfunction…

Risk Factor Modification: The Evidence Base for Primary Prevention

…and from secondary prevention, which addresses patients with established disease to reduce recurrent events and mortality. Risk factor modification is therefore directed at identifying individuals…

Acute coronary syndrome: quick reference for loading doses and time targets

…diagnostic ECG, the ECG must be repeated, particularly with ongoing or recurrent pain [1,3,4]. This quick reference gives internationally established doses. Drug availability…

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