…Presentation and Symptoms The clinical spectrum of ISR is broad: Many patients remain asymptomatic. The most common symptomatic presentation is CCS, usually with recurrent angina…

…on the extent of microvascular obstruction and the territory supplied by the treated vessel. Possible manifestations include: Persistent or recurrent myocardial ischemia Deterioration in ventricular…

…defining electrocardiographic feature is the absence of persistent ST segment elevation. This does not imply low risk: patients with NSTE ACS may have substantial myocardial…

…Hypoperfusion with persistent organ injury Consider mechanical circulatory support Refractory advanced disease Consider palliative care Right ventricular failure is characterized by increased right atrial and…

…and fibrin formation. Within a stented segment, thrombus may also develop because of disturbed flow, residual dissection, inadequate stent expansion, incomplete apposition, or persistent disease…

…Persistent bradycardia (< 40 beats/min) Undiagnosed systolic murmur Carotid sinus massage should be considered in patients with symptoms suggestive of carotid sinus syncope and…

…disease therefore does not establish a benign diagnosis. ANOCA/INOCA is associated with recurrent symptoms, impaired quality of life, repeated hospital presentations and angiography, and…

…hypertension, chronic ischemic heart disease, heart failure with reduced ejection fraction (HFrEF), and post myocardial infarction (MI) care. Despite their proven morbidity and mortality benefits…

…Endothelial dysfunction, coronary microvascular disease and vasospasm may coexist with atherosclerosis or may be the dominant cause of ischaemia. Other mechanisms capable of obstructing coronary…

…of lipid lowering treatment for patients with chronic coronary syndrome, acute coronary syndrome (ACS), atherosclerotic peripheral arterial disease, and other very high risk settings described…