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Risk Factor Modification: The Evidence Base for Primary Prevention

…while low educational attainment contributes materially to overall risk. The population impact of a risk factor depends not only on the relative risk associated with…

Colchicine and Anti-inflammatory Therapy in Coronary Disease

…lower C reactive protein, and impair neutrophil chemotaxis toward inflammatory sites. Its cardiovascular effects therefore appear to reflect modulation of vascular inflammation rather than lipid…

Bempedoic Acid: Evidence and Clinical Use

…significant relative and absolute reductions in four component major adverse cardiovascular events. The reported hazard ratio was 0.83, with a 95% confidence interval of…

Lipid-Lowering Therapy: Statins as First-Line Treatment

…improves endothelial function, lowers circulating high sensitivity C reactive protein, reduces thrombogenicity, and favourably modifies inflammatory and collagen related components of atherosclerotic plaque. These effects…

Pharmacologic agents in myocardial perfusion imaging

…They are contraindicated in patients with bronchospastic lung disease, or a history of significant reactive airway disease. Contraindications also include second degree or third degree…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…progressive, and highly complex lipid driven inflammatory disease of the arterial intima that serves as the fundamental pathophysiological substrate for acute coronary syndromes (ACS), including…

Cardiovascular effects of COVID-19 (Coronavirus Disease 2019)

…of which 69.4% died. Guo et al also report a significant association between troponin T levels and C reactive protein (CRP) and N terminal…

Metabolic Syndrome: Definition and Clinical Significance

…or visceral, adipose tissue is more closely related to insulin resistance and the risk of diabetes and cardiovascular disease than total adiposity alone. The waist…

Assessment of the pupillary reflex in cardiac arrest

…reactive pupil generally indicates an intact brainstem and adequate cerebral perfusion, whereas fixed, dilated pupils can signal severe global ischemia or even herniation of the…

Anaphylaxis: quick reference for emergency management

Akutsjukvård Lathundar Basic principle Anaphylaxis is a rapidly developing systemic hypersensitivity reaction that can cause life threatening compromise of the airway, breathing or circulation. Skin…

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