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Cardiac Rehabilitation After Myocardial Infarction

…mortality The modern concept of rehabilitation has evolved from early post infarction physical activity programmes into a structured centre of secondary cardiovascular prevention in which…

Resistant Hypertension: Evaluation and Treatment

…diabetes, or chronic kidney disease. Evaluation and Physical Examination The diagnostic assessment should establish that hypertension is genuine, identify potentially remediable causes, assess comorbidities and…

Chronic Heart Failure With Reduced Ejection Fraction: Four-Pillar Therapy

…is recurrent clinical deterioration despite careful follow up and appropriate therapy. In this setting, the risk of sudden death and end stage heart failure is…

Antianginal Therapy: Beta-Blockers, Calcium Channel Blockers, Nitrates, and Ranolazine

…uncomplicated acute coronary syndrome when LVEF is 40% is not definitive. Observational studies have yielded conflicting results, and the appropriate duration of therapy in p

Cardiovascular Risk in Women: Sex-Specific Factors

…cardiovascular impact in women. Obesity, physical inactivity and depression are more common in women. Dyslipidaemia, hypertension, diabetes and obesity become increasingly prevalent after the menopausal…

Carotid Artery Disease: Screening, Medical Therapy and Revascularisation

…hypercholesterolaemia, and sedentary behaviour; family history, particularly in the broader assessment of peripheral arterial and aortic disease; planned surgery, especially carotid endarterectomy (CEA), coronary artery…

Risk Factor Modification: The Evidence Base for Primary Prevention

…regular physical activity, avoidance of smoking, and adequate sleep. The process should begin early in life. Primordial prevention in childhood may reduce the subsequent development…

Refractory Angina: Options When Standard Therapy Fails

…despite the exhaustion of conventional therapeutic options. It is defined by symptoms lasting more than 3 months and attributable to established reversible myocardial ischaemia in…

Diuretic Strategy and Decongestion in Heart Failure

…and physical examination The objective of decongestion is clinical euvolemia rather than an isolated numerical change in weight. Assessment should integrate the history, physical examination…

Complete Versus Culprit-Only Revascularization in Acute Coronary Syndrome

…infarction Definition and pathophysiology In acute coronary syndrome (ACS) with multivessel coronary artery disease (MVD), revascularization may be directed exclusively at the infarct related artery…

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