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Massive haemorrhage and transfusion: quick reference

…major haemorrhage protocol early. Protocols improve above all the logistics, the communication and the simultaneous delivery of red cells, plasma and platelets. Observational data from…

Cardiac arrest during pregnancy and childbirth

…In circumstances of hypotension and hemorrhage, it is imperative to administer appropriate fluid or erythrocyte boluses to restore circulatory volume. To ensure optimal oxygen delivery…

Cardiovascular Risk in Women: Sex-Specific Factors

…management, treatment response and outcomes of cardiovascular disease. The biological differences between females and males arise partly from the chromosomal distinction between XX and XY…

🟠 Nitroprusside

…altered mental status and lactic acidosis). Fatal outcomes are rare. Renal failure increases risk of cyanide toxicity. Cyanide toxicity requires doses 2 μg/kg…

SGLT2 Inhibitors for Cardiovascular and Renal Protection

…cardiac metabolic efficiency, including increased oxygen delivery and beta hydroxybutyrate oxidation Reduced sodium hydrogen exchanger subtype 3 activity Attenuation of oxidative stress, inflammation and fibrosis…

A new ECG biomarker for sudden cardiac death

…At the other end, roughly two thirds of ICDs implanted for reduced LVEF never deliver an appropriate shock, so the false positive burden is substantial…

Heart Failure With Preserved Ejection Fraction: Diagnosis and Treatment

…cannot deliver blood at a rate appropriate to tissue requirements unless filling pressures are elevated. The syndrome is therefore defined by symptoms and signs of…

Assessment of the pupillary reflex in cardiac arrest

…was associated with a threefold increased risk of an adverse neurological outcome. In summary, while the absence of a pupillary reflex upon hospital admission post…

Physiological Assessment of Coronary Stenoses and Revascularization Decisions

…In parallel, large outcome trials have clarified, and in some cases substantially narrowed, the role of revascularization itself in stable coronary artery disease, while a…

Care after return of spontaneous circulation (ROSC)

…after ROSC or initiation of ECMO. The syndrome was first described by Negovsky , who identified four processes that defined the victim's outcome: Neurological injury…

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