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Myocardial Ischemia & infarction: Cellular changes, ECG and symptoms

ECG Myocardial ischemia and infarction Myocardial ischemia: cellular changes, ECG signs and development of infarction Like all other cells in the human body, cardiac myocytes…

ST-Elevation Myocardial Infarction: Diagnosis and Electrocardiographic Criteria

…symptoms or signs, with or without electrocardiographic changes, and with or without acute elevations in cardiac troponin concentrations. Based on the presenting electrocardiogram (ECG) and…

Acute Coronary Syndrome: Definitions and Initial Triage

…in isolation. The initial diagnosis and triage depend on integration of symptoms, vital signs, the ECG, and serial cardiac troponin measurements. Evaluation and physical examin

Unstable Angina: Definition and Contemporary Management

…with recent changes in symptoms or signs, with or without ECG abnormalities and with or without an elevation in cardiac troponin. The underlying pathological mechanism…

Hyponatraemia: quick reference for work-up and correction

…breathing and circulation. 2. Assess the neurological symptoms and at the same time exclude other acute causes, for example hypoglycaemia, poisoning, stroke, meningitis and a…

Secondary Hypertension: When and How to Investigate

…to investigate General indications Patients with suggestive signs, symptoms, or medical histories should undergo appropriate screening for secondary hypertension. The initial clinical assessment should establish:…

Atropine: Dosing in Bradycardia and Its Limitations

…50 beats per minute in the first 4 to 6 hours after an acute infarction—patients may develop hypotension and signs of end organ hypoperfusion…

Digoxin: Dosing, Therapeutic Range and Toxicity Management

…digoxin exerts significant systemic effects via the autonomic nervous system. It attenuates carotid sinus baroreceptor activity and acts centrally and peripherally to enhance vagal tone…

Left Main Coronary Artery Disease: Revascularisation Strategy

…The clinical evaluation includes: Symptom burden and functional limitation Evidence of heart failure Haemodynamic stability Diabetes status Renal dysfunction and other important comorbidities Frailty Liver…

Atrial Fibrillation in the Critically Ill Patient

…beyond the arrhythmia itself. It may cause symptoms and impaired quality of life, contribute to heart failure, and increase the risk of stroke and other…

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