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Cardiovascular Risk in Women: Sex-Specific Factors

…reproductive and pregnancy related history. Female specific or female predominant factors associated with later cardiovascular risk include: Premature menopause Premature ovarian insufficiency Hypertensive disorders of…

The Fourth Universal Definition of Myocardial Infarction: Types 1–5

…because myocardial injury may occur without myocardial ischaemia. Non ischaemic myocardial injury may accompany numerous cardiac and systemic disorders, including: Cardiac causes Systemic causes Heart…

Secondary Hypertension: When and How to Investigate

…blood pressure Other cardiovascular risk factors and relevant comorbidities Evidence of hypertension mediated organ damage Existing cardiac, cerebrovascular, or renal disease The possibility of a…

Cardiovascular Risk Assessment with SCORE2 and SCORE2-OP

…Risk estimation uses the appropriate sex specific and smoking specific table or calculator. The relevant BP and non high density lipoprotein cholesterol (non HDL C…

Familial and Genetic Screening in Premature Cardiovascular Disease

…hypertension and thromboembolic disorders. Most recognised heritable cardiovascular conditions demonstrate autosomal dominant transmission, in which an affected heterozygous individual has a 50% risk of transmitting…

Chest Pain in the Emergency Department: Diagnostic Pathways

…injury leads to release of cardiac troponin, but troponin elevation is not specific for myocardial infarction. Other conditions may produce cardiomyocyte injury and elevated troponin…

Invasive Coronary Angiography: Indications and Vascular Access

…intraluminal mass and lesion haziness raise suspicion of thrombus, although haziness is not specific. Intravascular imaging can identify plaque disruption, thrombus and other structural features…

Brugada syndrome: ECG, clinical features and management

…line with the disorder. There are however other disorders that may bring about similar ECG changes, and these are as follows: Arrhythmogenic right ventricular dysplasia…

Differential Diagnosis of Chest Pain: A Clinical Overview

…autoimmune disorder or known malignancy may suggest specific, nonidiopathic etiologies [2]. Summary of Pain Characteristics The following table synthesizes the key differential diagnoses and their…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…an inherited disorder characterized by persistently elevated plasma low density lipoprotein cholesterol (LDL C) from early life and a consequent excess risk of premature atherosclerotic…

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