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Cardiovascular Risk in Women: Sex-Specific Factors

…Female specific and female predominant risk factors Risk assessment should include reproductive and pregnancy related history. Female specific or female predominant factors associated with later…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…decade in males and approximately 10 years later in females. Untreated HoFH is associated with extensive premature and progressive ASCVD; CAD and aortic stenosis may…

Differential Diagnosis of Chest Pain: A Clinical Overview

…Associated Findings: Exertional dyspnea, dizziness, and syncope may also occur [5]. Non Cardiac Causes Several non cardiac conditions can present with chest pain that requires…

Stroke Prevention in Atrial Fibrillation: Choosing Anticoagulation

…stroke risk is increased approximately five fold, and AF is associated with roughly one in five strokes. Thrombus formation is most commonly related to the…

Atrial flutter: classification, causes, ECG criteria and management

…persons with significant heart disease, predominantly ischemic heart disease. However, most cardiac conditions may be associated with atrial flutter. As compared with several other supraventricular…

Stent Thrombosis: Timing, Causes, Diagnosis, and Prevention

…be specified. Coronary arterial thrombi are predominantly platelet rich because they form under high shear conditions. Disruption of an atherosclerotic plaque or injury associated with…

Brugada syndrome: ECG, clinical features and management

…than 12 genetic mutations have been associated with the Brugada syndrome. These mutations are located in genes encoding potassium and calcium channels of the outer…

Familial and Genetic Screening in Premature Cardiovascular Disease

…X linked condition may develop a phenotype later and require delayed or individualized assessment. Disease specific genetic architecture HCM is predominantly associated with variants affecting…

Acute Coronary Syndrome: Definitions and Initial Triage

…arrhythmias, and heart failure are among the conditions associated with myocardial injury. Relationship to chronic coronary syndromes Chronic coronary syndromes (CCS) describe stable period clinical…

Chest Pain in the Emergency Department: Diagnostic Pathways

…specific for myocardial infarction. Other conditions may produce cardiomyocyte injury and elevated troponin, so biomarker interpretation must be integrated with the clinical history, ECG, and…

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