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Antiplatelet Therapy in Secondary Prevention After Myocardial Infarction

…does not specify the loading dose. Efficacy and harms In secondary prevention trials involving patients with previous vascular disease, aspirin reduced the combined incidence of…

🟠 Aspirin (Acetylsalicylic acid)

…Interactions Pharmacodynamic interactions Anticoagulants, thrombolytics, or other platelet aggregation inhibitors: Salicylates inhibit platelet function and enhance the effect of anticoagulants, increasing bleeding risk. Monitor coagulation…

Smoking Cessation: Pharmacotherapy and Cardiovascular Benefit

…other inhaled nicotine products. In cardiovascular medicine, the objective is not merely to reduce cigarette consumption but to achieve complete abstinence from tobacco and ultimately…

ACE Inhibitor Cough and Angioedema: Practical Management

…the sensitization of sensory nerve endings due to the accumulation of bradykinin. ACE is responsible for metabolizing bradykinin and other tachykinins, such as substance P…

Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Multivessel Coronary Artery Disease

…underlying coronary atherosclerotic process. Their clinical effects therefore occur within the broader framework of guideline directed medical therapy and secondary prevention. PCI treats focal stenotic…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…also provides an opportunity to recognise atherosclerosis in other arterial territories and to initiate secondary prevention. Clinical assessment should include functional status and walking capacity…

Resistant Hypertension: Evaluation and Treatment

… Increased mortality; and A higher probability of secondary hypertension. Patients may also have comorbid features associated with a greater cardiovascular risk among those with resistant…

Colchicine and Anti-inflammatory Therapy in Coronary Disease

…Consequently, the decision to prescribe colchicine requires attention to the balance between reduction in ischaemic events and possible infectious or other non cardiovascular adverse outcomes…

Left Main Coronary Artery Disease: Revascularisation Strategy

…The extent of jeopardized myocardium Left ventricular systolic function Diabetes and other comorbidities Anatomical complexity and completeness of possible revascularization A proximal lesion jeopardizes more…

Levosimendan (Simdax, Simendan) in acute heart failure

…respect to either the primary or secondary outcomes. Primary outcome events occurred in 49% of patients in the milrinone group and 54% in the dobutamine…

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