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Ezetimibe: Place in Therapy and Expected LDL-C Reduction

…LDL C reduction required is greater than can reasonably be obtained with a statin alone but does not necessarily require the larger effect of a…

Alcohol withdrawal and delirium tremens: quick reference

Psykiatri Akutsjukvård Lathundar Rapid summary Alcohol withdrawal occurs after an abrupt reduction or cessation of prolonged and heavy alcohol intake. The condition can develop despite…

Acute Limb Ischaemia: Recognition and Urgent Management

…and pathophysiology Acute limb ischaemia (ALI) is an abrupt reduction in arterial perfusion of an upper or lower limb that causes tissue metabolic requirements to…

LDL Cholesterol Targets Across Cardiovascular Risk Categories

…depends on baseline cardiovascular risk and the magnitude of LDL C reduction. Thus, even a modest absolute reduction may be clinically important in individuals at…

Antiplatelet Therapy in Secondary Prevention After Myocardial Infarction

…although the overall reduction in ischaemic events outweighed the increase in serious bleeding in the populations studied. There was no evidence of a different aspirin…

Aspirin in Primary Prevention: Current Recommendations

…sex in the overall trial analyses. Some data from a study of healthy women suggested a reduction in ischaemic stroke, particularly among women with stroke…

Hypertensive Emergency and Urgency: Differentiation and Treatment

…of vascular autoregulation during a rapid or severe rise in BP. This may produce acute injury in the brain, retina, heart, aorta, kidneys, or other…

Smoking Cessation: Pharmacotherapy and Cardiovascular Benefit

…risk falls within five years of stopping but may remain elevated thereafter. The overall health benefit is greater still when reductions in non cardiovascular morbidity…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…progressive reduction of coronary blood flow sufficient to produce myocardial ischaemia and, when prolonged or severe, myocardial necrosis. It most commonly reflects atherothrombosis: disruption of…

Myocardial Ischemia & infarction: Cellular changes, ECG and symptoms

…and infarction Myocardial ischemia: cellular changes, ECG signs and development of infarction Like all other cells in the human body, cardiac myocytes use ATP (adenosine…

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