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Atrial flutter: classification, causes, ECG criteria and management

…predominantly ischemic heart disease. However, most cardiac conditions may be associated with atrial flutter. As compared with several other supraventricular tachyarrhythmias, atrial flutter does not…

Familial and Genetic Screening in Premature Cardiovascular Disease

…Familial and genetic screening in cardiovascular medicine is the systematic assessment of relatives and other individuals who may carry an inherited predisposition to cardiovascular disease…

Interpreting NT-proBNP and BNP in Clinical Decision-Making

…cardiac amyloidosis Sepsis and other hyperdynamic states In cardiac amyloidosis, BNP or NT proBNP may be markedly elevated even when overt congestion is not apparent…

Arrhythmogenic Right Ventricular Cardiomyopathy / Dysplasia (ARVC, ARVD)

…Cardiomyopathy / Dysplasia (ARVC, ARVD) Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is considered a genetic cardiomyopathy that predominantly affects the right ventricle. ARVC is defined by the…

Bempedoic Acid: Evidence and Clinical Use

…is a prodrug activated predominantly in the liver by very long chain acyl CoA synthetase 1. This activating enzyme is not expressed in skeletal muscle…

In-Stent Restenosis: Mechanisms and Treatment

…although its resolution does not consistently permit identification of foamy macrophages. The occurrence of neoatherosclerosis helps explain why ISR and other stent related events may…

Stent Thrombosis: Timing, Causes, Diagnosis, and Prevention

…stent implantation should always be specified. Coronary arterial thrombi are predominantly platelet rich because they form under high shear conditions. Disruption of an atherosclerotic plaque…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…permeability of the endothelium to circulating apolipoprotein B (ApoB) containing lipoproteins, predominantly low density lipoprotein cholesterol (LDL C) [3] . Once trapped within the subendothelial space…

Fractional Flow Reserve and Non-Hyperaemic Pressure Ratios

…may therefore be discordant. A reduced FFR with preserved CFR suggests a predominantly focal epicardial lesion that may not be strongly flow limiting. In contrast…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…the aorta or arteries supplying the limbs. In adults over 40 years of age, atherosclerosis is the predominant cause. Other mechanisms include thrombosis, embolism, vasculitis…

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