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Vasospastic (Prinzmetal) Angina: Provocation Testing and Treatment

…vasoconstriction of one or more coronary arteries. Epicardial spasm produces a reversible functional occlusion and usually causes transmural ischaemia. The resulting abnormalities in left ventricular…

Type 2 Myocardial Infarction: Mechanisms and Management

…include fixed coronary atherosclerosis without plaque rupture, coronary artery spasm, coronary microvascular dysfunction (encompassing endothelial dysfunction, smooth muscle cell dysfunction, and dysregulation of sympathetic innervation)…

Acute exacerbation of COPD: quick reference

…Akutsjukvård Lathundar Key messages Two things set the COPD exacerbation apart from many other causes of acute dyspnoea: oxygen must be titrated cautiously and the…

Anthropometric measurements

…population measure that performs poorly at the level of the individual: it does not distinguish muscle from fat and takes no account of fat distribution…

Introduction to cardiac arrest

…10 such victims, the heart in 6 or 7 showed no recent disease in coronary arteries or in heart muscle. In other words, the heart…

Renal parameters

…halve before the creatinine leaves the reference range, because the relationship is hyperbolic. In people with a low muscle mass — the elderly, the undernourished, amputees…

Acute Limb Ischaemia: Recognition and Urgent Management

…and venous filling may be reduced. Other possible findings include muscle stiffening and loss of deep tendon reflexes. Pulses are absent distal to the obstruction…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

…multiple arterial territories. The arterial wall is biologically active. Endothelial and smooth muscle cells normally regulate vascular tone, preserve an antithrombotic surface, and control the…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…or arteries supplying the limbs. In adults over 40 years of age, atherosclerosis is the predominant cause. Other mechanisms include thrombosis, embolism, vasculitis, fibromuscular dysplasia…

Primary Aldosteronism: Screening and Management

…transport—MRs are also present in cardiac myocytes, vascular smooth muscle, endothelial cells, macrophages, neurons and other tissues. This distribution helps explain why PA produces…

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