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Secondary Hypertension: When and How to Investigate

…Whether hypertension is genuinely present Factors that may be contributing to elevated blood pressure Other cardiovascular risk factors and relevant comorbidities Evidence of hypertension mediated…

Resistant Hypertension: Evaluation and Treatment

…In clinical practice, the condition is identified primarily through persistently elevated blood pressure despite multidrug treatment rather than through specific symptoms. The clinical importance lies…

Blood Pressure Targets in Older and Frail Adults

…Ageing is associated with progressive increases in systolic blood pressure (SBP), while diastolic blood pressure (DBP) rises less steeply and may remain stable or decline…

🟠 Mean arterial pressure (MAP) calculator

…and vascular resistance. Advantages of measuring MAP over systolic blood pressure While systolic blood pressure (SBP) indicates the maximum pressure during heart contraction, it does…

Chronic Kidney Disease as a Cardiovascular Risk Factor

…renal disease are bidirectionally related: hypertension accelerates CKD progression, while impaired renal function further increases blood pressure. Non traditional cardiovascular mechanisms include: Uraemia associated inflammation…

Interpretation of myocardial perfusion images (Myocardial SPECT / PET)

…further classified based on the intensity of tracer uptake and associated myocardial changes: Mild defects : Characterized by decreased tracer counts while preserving normal wall thickness…

Atrial Fibrillation in the Critically Ill Patient

…an elevated cardiac troponin concentration and new ST segment depression in new onset AF should not automatically be labelled type 2 myocardial infarction without further…

🟠 Ticagrelor (Brilinta, Brilique)

…administration, warnings, precautions, and other relevant information for the drug Ticagrelor . Table 1 Summary Indications Ticagrelor, in combination with acetylsalicylic acid (ASA), is indicated for…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…and pathophysiology Familial hypercholesterolaemia (FH) is an inherited disorder characterized by persistently elevated plasma low density lipoprotein cholesterol (LDL C) from early life and a…

LDL Cholesterol Targets Across Cardiovascular Risk Categories

…particularly in patients with: Diabetes or other cardiometabolic risk factors Obesity Insulin resistance or metabolic syndrome Elevated triglycerides Low or apparently well controlled LDL C…

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