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Interpretation of myocardial perfusion images (Myocardial SPECT / PET)

…further classified based on the intensity of tracer uptake and associated myocardial changes: Mild defects : Characterized by decreased tracer counts while preserving normal wall thickness…

Causes of sudden cardiac arrest

…degree of ischemia, parasympathetic and sympathetic tone) while others take months or years to develop (e.g. myocardial remodeling in heart failure or after myocardial…

Atrial Fibrillation in the Critically Ill Patient

…In DHF, ventricular rate may decrease as dyspnoea improves and sympathetic activation subsides, making it difficult to determine whether AF initiated the deterioration or resulted…

Ezetimibe: Place in Therapy and Expected LDL-C Reduction

…By reducing intestinal cholesterol absorption, it decreases the quantity of cholesterol delivered to the liver. The resulting hepatic response includes increased expression of low density…

Doppler effect and Doppler echocardiography

…the blood cells (primarily erythrocytes) and tissues (primarily myocardium). The Doppler principle, however, remains unchanged: when the sound source and reflectors move towards each other…

Inclisiran and Emerging Lipid-Lowering Agents

…hepatocytes. Reduced hepatic PCSK9 synthesis decreases circulating PCSK9, increases the availability of hepatic low density lipoprotein cholesterol (LDL C) receptors at the cell surface, and…

ECG changes due to electrolyte imbalance (disorder)

…electrolyte imbalances are clinically negligible (from an electrophysiological standpoint), whereas others may be life threatening. The most common and clinically most relevant electrolyte imbalances concern…

ACE Inhibitor Cough and Angioedema: Practical Management

…these adverse events are related to the suppression of the renin angiotensin aldosterone system (RAAS), such as decreases in blood pressure and mild azotemia. However…

Interpretation of neonatal and pediatric electrocardiograms (ECG)

…of the nine parameters listed above. Many of the diagnoses mentioned below are discussed in detail in other chapters, to which links are provided throughout…

Adenosine: Administration Technique, Dose Escalation and Precautions

…in turn reduces the L type calcium current (Ica.L) and the pacemaker current (If) in sinus node cells, accompanied by a decrease in Vmax…

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