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Brugada syndrome: ECG, clinical features and management

…necessary to develop the disorder. Till now (2016) more than 12 genetic mutations have been associated with the Brugada syndrome. These mutations are located in…

Familial and Genetic Screening in Premature Cardiovascular Disease

…X linked condition may develop a phenotype later and require delayed or individualized assessment. Disease specific genetic architecture HCM is predominantly associated with variants affecting…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…250–300 people and is the most common inherited metabolic disorder associated with premature cardiovascular disease. Prevalence is higher in populations with a founder effect…

Atrial flutter: classification, causes, ECG criteria and management

…persons with significant heart disease, predominantly ischemic heart disease. However, most cardiac conditions may be associated with atrial flutter. As compared with several other supraventricular…

Coronary Anomalies and Myocardial Bridging

…treated in the same broad category as a patient with coronary artery disease when clinically appropriate. Other coronary anomalies Anomalous coronary origin and course can…

Acute Coronary Syndrome: Definitions and Initial Triage

…takotsubo cardiomyopathy, valvular disease, arrhythmias, and heart failure are among the conditions associated with myocardial injury. Relationship to chronic coronary syndromes Chronic coronary syndromes (CCS…

Differential Diagnosis of Chest Pain: A Clinical Overview

…chest discomfort requires a systematic differential diagnosis, as the syndrome associated with ischemic heart disease is broader than chest pain itself, encompassing symptoms like tightness…

Chest Pain in the Emergency Department: Diagnostic Pathways

…not specific for myocardial infarction. Other conditions may produce cardiomyocyte injury and elevated troponin, so biomarker interpretation must be integrated with the clinical history, ECG…

ECG manifestations of left main coronary artery (LMCA) occlusion and critical stenosis

…opportunity for reperfusion. In addition, some patients present with severe LMCA stenosis exacerbated by other conditions, and these must also be recognized. Prompt identification of…

Cardiac arrest due to hypoxia and asphyxia

…Respiratory conditions : Tension pneumothorax Drowning Airway obstruction Hanging Pneumonia High altitude sickness Aspiration Chronic obstructive pulmonary disease (COPD) Bronchospasm (asthma) Other : Coma Central hypoventilation syndromes…

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