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Familial and Genetic Screening in Premature Cardiovascular Disease

…Familial and genetic screening in cardiovascular medicine is the systematic assessment of relatives and other individuals who may carry an inherited predisposition to cardiovascular disease…

Cardiovascular Risk Assessment with SCORE2 and SCORE2-OP

…of the overall burden of atherosclerotic cardiovascular disease. SCORE2 is intended principally for adults aged 40–69 years, whereas SCORE2 OP is used in adults…

Cardiovascular Risk in Women: Sex-Specific Factors

…risk enhancing conditions and are more prevalent in women. Chronic kidney disease and several other comorbidities also contribute to the disproportionate cardiovascular burden in women…

Primary Aldosteronism: Screening and Management

…in severe cases, periodic paralysis. Nevertheless, many patients are normokalaemic and have no distinctive symptoms attributable to aldosterone excess. Cardiovascular complications may dominate the presentation…

Secondary Hypertension: When and How to Investigate

…elevated blood pressure Other cardiovascular risk factors and relevant comorbidities Evidence of hypertension mediated organ damage Existing cardiac, cerebrovascular, or renal disease The possibility of…

🟠 Aspirin (Acetylsalicylic acid)

…Use Aspirin with caution in the following cases: Concurrent anticoagulant therapy (e.g., coumarin derivatives or heparin—except low dose heparin). Patients with gastrointestinal disorders…

Smoking Cessation: Pharmacotherapy and Cardiovascular Benefit

…smokers for a prolonged period. In heavy smokers, cardiovascular risk falls within five years of stopping but may remain elevated thereafter. The overall health benefit…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…coronary, cerebrovascular or other peripheral arterial disease, and management should therefore address the entire arterial circulation. PAD is associated with increased cardiovascular morbidity and mortality…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…approximately 1 in 250–300 people and is the most common inherited metabolic disorder associated with premature cardiovascular disease. Prevalence is higher in populations with…

No-Reflow Phenomenon During Percutaneous Coronary Intervention: Prevention and Treatment

…It is therefore a disorder of coronary microvascular perfusion rather than persistent obstruction of the treated epicardial segment. The phenomenon occurs in approximately 2%–3…

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