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Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

Cardiology Myocardial ischemia and infarction Definition and pathophysiology Atherosclerosis is a chronic, inflammatory disease of the arterial wall in which lipid accumulation, vascular cell dysfunction…

Complications of Coronary Angiography and Vascular Access Management

…been identified as important risk factors. Severe atherosclerosis of the axillary or subclavian arteries may increase the risk of embolization. Risk assessment should be individualized…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

Cardiology Coronary Atherosclerosis Coronary atherosclerosis is a chronic, progressive, and highly complex lipid driven inflammatory disease of the arterial intima that serves as the fundamental…

Smoking Cessation: Pharmacotherapy and Cardiovascular Benefit

…modifiable driver of atherosclerosis and cardiovascular disease. Its relationship with cardiovascular risk is nonlinear: even light smoking carries a substantial proportion of the excess ischaemic…

Carotid Artery Disease: Screening, Medical Therapy and Revascularisation

…components of assessment. The history should include: previous TIA or stroke; symptoms suggesting current or recent cerebral ischaemia; known CAD, PAD, or other atherosclerotic disease…

Coronary Artery Disease

…terms refer to symptomatic coronary atherosclerosis. Traditional classification of coronary artery disease Traditionally, coronary artery disease has been classified into the following three syndromes: Stable…

Stable Coronary Artery Disease (Angina Pectoris): Diagnosis, Evaluation, Management

…terms refer to symptomatic coronary atherosclerosis. Traditional classification of coronary artery disease Traditionally, coronary artery disease has been classified into the following three syndromes: Stable…

Colchicine and Anti-inflammatory Therapy in Coronary Disease

…colchicine requires attention to the balance between reduction in ischaemic events and possible infectious or other non cardiovascular adverse outcomes. Mechanisms of action Colchicine Colchicine…

Myocardial Ischemia & infarction: Cellular changes, ECG and symptoms

…atherosclerotic arteries. This engenders the typical ECG changes as well. In acute coronary syndromes, however, symptoms and ECG changes are manifest at rest because of…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…years of age, atherosclerosis is the predominant cause. Other mechanisms include thrombosis, embolism, vasculitis, fibromuscular dysplasia, arterial entrapment, cystic adventitial disease and trauma. Atherosclerotic PAD…

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