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Bempedoic Acid: Evidence and Clinical Use

…Pharmacology & dosing Definition and pharmacological rationale Bempedoic acid is an oral, small molecule lipid lowering agent used to reduce low density lipoprotein cholesterol (LDL C)…

Dual Antiplatelet Therapy Duration After Acute Coronary Syndromes and Elective Percutaneous Coronary Intervention

…DAPT) is the combined use of aspirin and an oral P2Y12 receptor inhibitor. It is central to the prevention of platelet mediated coronary thrombosis after…

SGLT2 Inhibitors for Cardiovascular and Renal Protection

…inhibitors are a class of oral agents initially developed for glucose lowering in type 2 diabetes mellitus (T2DM). The principal drugs identified in the source…

Amiodarone: Loading, Maintenance Dosing and Monitoring Schedule

…Oral doses sufficient to control arrhythmias do not depress left ventricular ejection fraction (LVEF), even in patients with reduced LVEF. However, due to its antiadrenergic…

Corticosteroids: quick reference for dose equivalents and stress dosing

…or triple the oral daily dose during the days of illness (the patient's sick day rules) Vomiting or diarrhoea, unable to keep tablets down…

Empirical antibiotic therapy: quick reference for common infections

…days Hospital acquired pneumonia, non severe cefotaxime 1–2 g × 3 IV 8 days including oral step down Hospital acquired pneumonia, severe piperacillin–tazobactam 4…

Hypertensive crisis: drugs and doses

…organ damage. Isolated malignant retinopathy without other acute organ damage can often be treated more cautiously with oral drugs under careful observation [3,4]. A…

Hypertensive crisis: quick reference for acute blood pressure lowering

…pressure without acute organ damage should as a rule not be lowered rapidly with intravenous drugs. Restart or optimise oral treatment and ensure follow up…

Opioids in acute pain: quick reference for dosing and conversion

…not to a schedule. Always prescribe a laxative and an antiemetic as required at the same time as the opioid. Approximate equianalgesic conversion Opioid Oral…

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