…established. Limited data are available for children with sickle cell anemia. Method of Administration Route : Oral. Prasugrel can be taken with or without food. Administering…

…for the first week. Indications A mechanical valve prosthesis — warfarin is mandatory, and direct oral anticoagulants (DOACs) are contraindicated. Antiphospholipid syndrome, particularly triple positive disease…

…often ICU Usually outpatient Initial treatment Carefully titrated intravenous therapy when indicated Oral treatment and prompt follow up Main risk of management Overtreatment may impair…

…and bicarbonate , review the medication list (metformin, NSAIDs, RAAS blockade, gabapentin, direct oral anticoagulants) and refer to nephrology at an eGFR < 30, with rapid…

…full target doses of ACE inhibitors are reached. Medication doses should be increased to target as tolerated. Higher doses are more effective than lower doses…

…advanced age, and the use of certain medications or alcohol. Interpretation of HAS BLED score A score of 0 1 indicates low risk A score…

…anticoagulation is highly effective in reducing stroke risk. Wrfarin and novel oral anticoagulants can reduce the risk of stroke by 70%, as compared with placebo…

Cardiology Pharmacology & dosing Definition and pharmacological rationale Bempedoic acid is an oral, small molecule lipid lowering agent used to reduce low density lipoprotein cholesterol (LDL…

Myocardial ischemia and infarction Pharmacology & dosing Definition and pathophysiology Dual antiplatelet therapy (DAPT) is the combined use of aspirin and an oral P2Y12 receptor inhibitor…