Cardiology Pharmacology & dosing Definition and pharmacological rationale Bempedoic acid is an oral, small molecule lipid lowering agent used to reduce low density lipoprotein cholesterol (LDL…

…30–60 minutes and persists for up to 7 days after discontinuation because platelet inhibition is irreversible. Aspirin acts through only one platelet activation pathway…

…pharmacological basis Sodium glucose cotransporter 2 (SGLT2) inhibitors are a class of oral agents initially developed for glucose lowering in type 2 diabetes mellitus (T2DM)…

…plasma concentrations correlate well with oral doses, averaging approximately 0.5 mg/L (0.5 µg/mL) for each 100 mg/day at doses between…

…Sources Endocrine Society clinical practice guideline on the diagnosis and treatment of primary adrenal insufficiency. The summary of product characteristics for each glucocorticoid preparation. Internetmedicin…

…8 days including oral step down Hospital acquired pneumonia, severe piperacillin–tazobactam 4 g × 4 IV Exacerbation of COPD with an indication for antibiotics amoxicillin…

…important precautions. A hypertensive emergency is defined by a markedly raised blood pressure in combination with new or progressive acute target organ damage. Common manifestations…

…from a previously low level can cause organ damage at lower values, for example in pregnancy, acute glomerular disease or scleroderma renal crisis [1,2]…

…be documented when the drug is started. Sources WHO guidelines on the pharmacological management of pain. The summary of product characteristics for each opioid preparation.