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Atrial fibrillation: quick reference for emergency management

…or risk factors present An anticoagulant before cardioversion, or alternatively transoesophageal echocardiography. Cardioversion without preceding anticoagulation is reserved for CHA₂DS₂ VA 0–1 48 hours…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…undergoing angiography, approximately 10% have no critical epicardial stenosis. In some of these patients, microvascular obstruction or epicardial spasm may account for the ischaemia. STEMI…

Aspirin in Primary Prevention: Current Recommendations

…with risk increasing particularly after 70 years Male sex Previous upper gastrointestinal disease Hepatic or renal disease Multiple cardiovascular risk factors Concomitant nonsteroidal anti inflammatory…

Stroke Prevention in Atrial Fibrillation: Choosing Anticoagulation

…pathophysiology Atrial fibrillation (AF) is a major independent risk factor for thromboembolism, including ischaemic stroke. This risk applies across the clinical patterns of AF—paroxysmal…

CME: How dietary fat affects coronary arteries, LDL cholesterol and body weight

…hazards. For example, high HDL cholesterol levels appears to be beneficial, whereas triglyceride levels seem to be of little or no importance for atherosclerosis. When…

Myocardial Infarction with Non-Obstructive Coronary Arteries: Causes, Work-up and Management

…smoking may be present despite relatively few other conventional atherosclerotic risk factors. A substantial proportion present with NSTEMI, although STEMI occurs in approximately one third…

Antianginal Therapy: Beta-Blockers, Calcium Channel Blockers, Nitrates, and Ranolazine

…or combinations of these mechanisms. Drug selection can therefore be tailored to the suspected mechanism. No antianginal class has demonstrated consistent superiority for symptom relief…

Statin Intolerance and Statin-Associated Muscle Symptoms

…No single diagnostic test can distinguish a pharmacological SAMS effect from a nocebo response. Predisposing factors The likelihood of SAMS increases with higher statin doses…

Coronary Artery Disease

…dynamic disease. The majority of individuals in high income countries have some degree of coronary atherosclerosis. Risk factors for atherosclerosis (e.g smoking, hypertension, diabetes…

Stable Coronary Artery Disease (Angina Pectoris): Diagnosis, Evaluation, Management

…dynamic disease. The majority of individuals in high income countries have some degree of coronary atherosclerosis. Risk factors for atherosclerosis (e.g smoking, hypertension, diabetes…

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