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Carotid Artery Disease: Screening, Medical Therapy and Revascularisation

Cardiology Neurology Definition and Pathophysiology Carotid artery stenosis is an atherosclerotic narrowing of the carotid arteries. It forms part of multisite artery disease, defined as…

In-Stent Restenosis: Mechanisms and Treatment

Myocardial ischemia and infarction Definition and Clinical Significance In stent restenosis (ISR) is recurrent narrowing within a previously implanted coronary stent. It represents a form…

Left Main Coronary Artery Disease: Revascularisation Strategy

Myocardial ischemia and infarction Definition and Pathophysiology Left main coronary artery disease (LMCAD) refers to atherosclerotic narrowing of the left main coronary artery, which supplies…

Coronary Anatomy and Segmental Classification for the Clinician

…a left main coronary stenosis of at least 50% is considered significant. These thresholds describe luminal narrowing, not necessarily the physiological effect of the lesion…

Coronary Anomalies and Myocardial Bridging

…myocardium compresses the tunnelled coronary segment, producing an apparent angiographic narrowing. The narrowing generally improves or disappears during diastole, distinguishing myocardial bridging from a fixed…

Invasive Coronary Angiography: Indications and Vascular Access

…do not always correspond. Visual estimation of luminal narrowing may therefore be insufficient when deciding whether an intermediate lesion should be revascularized. Coronary pressure assessment…

Unstable Angina: Definition and Contemporary Management

…therefore be considered throughout assessment. Coronary disease is most commonly related to atheromatous plaque producing progressive narrowing or obstruction of epicardial coronary arteries. Endothelial dysfunction…

Pulmonary stenosis

…The stenosis is subvalvular, causing a narrowing of the RVOT (right ventricular outflow tract). Carcinoid heart disease : Carcinoid syndrome is a paraneoplastic syndrome that occurs…

Fractional Flow Reserve and Non-Hyperaemic Pressure Ratios

…Conversely, some lesions with apparently lesser narrowing are physiologically important. Lesion location also matters: stenoses in the left main stem or proximal left anterior descending…

Spontaneous Coronary Artery Dissection

…usually readily recognized Type 2 Long, smooth, diffuse luminal narrowing, typically extending more than 20–30 mm The most common pattern; may be mistaken for…

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