…systemic lupus erythematosus (SLE), systemic sclerosis, vasculitides, mixed connective tissue disease, myositis, Sjögren syndrome, gout and antiphospholipid syndrome (APS). Collectively, these disorders are associated with…

…Statins inhibit 3 hydroxy 3 methylglutaryl coenzyme A reductase, the rate limiting enzyme in cholesterol synthesis. Reduced hepatic cholesterol production increases hepatic LDL receptor expression…