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Principles of myocardial perfusion imaging (SPECT, PET), coronary blood flow and flow reserve (CFR)

…of 50 120 mmHg. This process is primarily mediated by local metabolic mechanisms, which adjust vascular tone in response to myocardial oxygen demand, and myogenic…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…The presence of tendon xanthomas, corneal arcus and xanthelasma. Potential secondary causes of hypercholesterolaemia. The likelihood of a monogenic disorder and the need for family…

Brugada Syndrome: Diagnosis & SCD Prevention

…prevention of SCD in Brugada syndrome. Pathophysiology and Genetic Architecture Genetic Architecture: From Monogenic to Polygenic Models Brugada syndrome was classically defined as a monogenic…

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