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Blood gas interpretation: quick reference for acid-base disorders

…or a mixed metabolic and respiratory acidosis if the pCO₂ is not low enough High Low Normal or low Respiratory alkalosis High High High Metabolic…

Cardiovascular Risk in Inflammatory and Autoimmune Disease

…systemic sclerosis, vasculitides, mixed connective tissue disease, myositis, Sjögren syndrome, gout and antiphospholipid syndrome (APS). Collectively, these disorders are associated with excess cardiovascular disease (CVD…

Ivabradine: Indications, Dosing and Heart-Rate Targets

…sinoatrial node pacemaker cells. This current is a mixed inward Na⁺/K⁺ current activated by hyperpolarisation and contributes to spontaneous diastolic depolarisation. By inhibiting the…

Liver parameters

…R < 2 cholestatic injury, and 2–5 a mixed pattern. Orders of magnitude that direct the work up ALT 50 × the upper limit of…

Poisoning: quick reference for antidotes and initial management

…release preparations, mixed poisoning, pregnancy, children, a need for an antidote or dialysis, and whenever the clinical course deviates from what was expected. The poison…

🟠 Drug-Induced Cardiotoxicity

…most major adverse cardiovascular events (MACE) severe ARISTADA ARIPIPRAZOLE LAUROXIL aripiprazole lauroxil Mixed wp less hypotension/ tachycardia mild Signifor LAR PASIREOTIDE PASIREOTIDE Arrhythmia wp most…

🟠 Ticagrelor (Brilinta, Brilique)

…mixed in half a glass of water, and consumed immediately. The mixture can also be administered via a nasogastric tube. Warnings and Precautions Increased risk…

Vasovagal Syncope: Diagnosis, Tilt Testing and Treatment

…cardiac output and a potential paradoxical vasodilation with hypotension occur, often accompanied by bradycardia. Most cases involve a mixed response of both hypotension and bradycardia…

Delirium in older adults: quick reference

…reduced eye contact Common and particularly easy to miss. May be misinterpreted as fatigue, depression or dementia Mixed Alternates between hypoactivity and hyperactivity Common on…

Diabetic ketoacidosis and hyperosmolar hyperglycaemic state: quick reference

…L Stupor or coma may occur Mixed picture of DKA and HHS Overlap is common. Treat as mixed DKA and HHS if the patient has…

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