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Cardiac amyloidosis

Cardiology Genetic and miscellaneous conditions Clinical Red Flags Raising Suspicion of Cardiac Amyloidosis Demographic and Clinical Context Cardiac amyloidosis should be suspected in patients older…

Coronary Anomalies and Myocardial Bridging

Cardiology Genetic and miscellaneous conditions Definition and classification Coronary anomalies are congenital abnormalities involving the origin, course, distribution, or termination of the coronary arteries. They…

Familial and Genetic Screening in Premature Cardiovascular Disease

…Consequently, a normal examination or cardiac investigation at one point in time does not reliably exclude future disease in an at risk relative. Across inherited…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…may include manifestations of coronary, cerebral or peripheral arterial disease, although the source material does not specify symptom patterns in detail. Physical manifestations Tendinous xanthomas…

ECG J wave syndromes: hypothermia, early repolarization, hypercalcemia & Brugada syndrome

ECG Genetic and miscellaneous conditions J wave syndromes: early repolarization pattern, Brugada syndrome, hypercalcemia and hypothermia The J wave – also referred to as Osborn's…

Eletrical alternans: the ECG in pericardial effusion & cardiac tamponade

ECG Genetic and miscellaneous conditions Eletrical alternans: an ECG sign of pericardial effusion and cardiac tamponade The pericardial space (cavity) always contains a small amount…

Pericarditis, myocarditis & perimyocarditis: ECG, criteria & treatment

ECG Genetic and miscellaneous conditions Pericarditis, myocarditis and perimyocarditis: ECG changes and clinical features The pericardium is a double walled sac in which the heart…

Takotsubo cardiomyopathy (broken heart syndrome, stress induced cardiomyopathy)

ECG Genetic and miscellaneous conditions Takotsubo cardiomyopathy (broken heart syndrome, apical ballooning syndrome, stress induced cardiomyopathy) Takotsubo cardiomyopathy (broken heart syndrome) is a rather peculiar…

Brugada syndrome: ECG, clinical features and management

Arrhythmias and arrhythmology ECG Genetic and miscellaneous conditions Brugada syndrome: A life threatening arrhythmia with unknown prevalence Pedro Brugada and his two brothers, Josep and…

Early repolarization pattern on ECG (early repolarization syndrome)

…ECG and ventricular fibrillation or sudden cardiac arrest is referred to as early repolarization syndrome . Early repolarization pattern may actually not be due to early…

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