…The selectivity for vascular smooth muscle means felodipine lacks the nodal effects of verapamil and diltiazem — no bradycardia, no AV block, and no clinically significant…

…and most oral anaerobes remain sensitive, and the resistance situation is favourable compared to almost all other countries. Time-dependent killing means that the dosing…

…APL Concentrated carbohydrate solution for acute hypoglycaemia The first-line treatment for severe hypoglycaemia in a patient who cannot swallow and in whom intravenous access…

…relief in nocturia and nocturnal enuresis, and haemostatic release of von Willebrand factor and factor VIII. Selectivity for the V2 receptor means it lacks the…

…is slowed. The half-life of a few seconds means both the effect and side effects are over before one can regret it, but requires…

…plasminogen activator (rt-PA) Fibrin-specific plasminogen activator that dissolves fresh thrombus and is the standard thrombolytic for ischaemic stroke and haemodynamically significant pulmonary embolism…

…minutes and a duration of 3–5 hours; intravenously the half-life is a few minutes, which makes the infusion fully controllable but also means…

…and the one with the least cardiovascular risk at a low dose. A short half-life of around 2 hours means the effect arrives and…

…that covers the basal insulin requirement between meals and overnight, with a largely flat profile over 24 hours and therefore a lower risk of nocturnal…

…inhibitor with fixed dosing and no routine monitoring. Lower risk of intracranial haemorrhage than warfarin — but the short half-life means a missed dose has…

…injection, and the long biological duration means a single dose suffices. Potency is approximately 25 times that of hydrocortisone and mineralocorticoid effect is absent, making…

…inotropy when the problem is the pump and not vascular tone. Strong β₁ effect with marked β₂ effect means that stroke volume increases while systemic…