…elimination from well perfused tissues. This is followed by a terminal half life of 26 to 107 days (mean 53 days, with most patients in…

…Maintenance dose : 5 mg once daily. Rationale: Patients in this age group have higher bleeding risk and increased exposure to the active metabolite of prasugrel…

…concentration monitoring Drug Comment : : Vancomycin (intravenous) Loading dose by weight, maintenance dose by renal function and drug concentration Gentamicin and other aminoglycosides A single dose…

…cover the baseline physical examination of patients prior to sotalol initiation. Diagnostics Electrocardiography (ECG) Electrocardiographic monitoring is central to the safe initiation and maintenance of…

…protocols. Note that while cardioversion restores sinus rhythm in up to 95% of patients, long term maintenance (particularly in persistent AF) remains the greater challenge.

…a loading dose followed by maintenance treatment. The source material does not specify the loading dose. Efficacy and harms In secondary prevention trials involving patients…

…the Life Course Primordial prevention Primordial prevention seeks to prevent the emergence of risk factors. It includes maintenance of favourable blood pressure, body mass index…

…burden, although improved metabolic and risk factor management has been associated with reduced AF symptoms and better maintenance of sinus rhythm in cohort studies. Obesity…

…re entry or triggered activity. All types of myocardial cells may be engaged in initiation and maintenance of this arrhythmia. As mentioned above VT causes…

…interpreting platelet function tests for HIT. Other cosiderations Based on a relationship observed in the PLATO study between the maintenance dose of ASA and the

…degree sinoatrial block implies that no impulses are conducted from the sinoatrial node to the atrium. Hence, the maintenance of cardiac rhythm (and thus life)…