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Cardiac amyloidosis

…1]. Cardiac Signs and Symptoms Patients often present with symptoms of predominant right heart failure, including lower extremity edema, ascites, and hepatic enlargement [8, 10…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…than an isolated disorder of the lower limbs. Patients frequently have concomitant coronary, cerebrovascular or other peripheral arterial disease, and management should therefore address the…

Incretins in Cardiometabolic Medicine: Leveraging GLP-1, GIP, and Glucagon Receptor Agonism for Cardiovascular Risk Reduction

…considered extremely difficult across patient categories. However, the emergence of incretin based therapies, starting with glucagon like peptide 1 receptor agonists (GLP 1 RAs) and…

Obesity and Cardiovascular Disease: Assessment and Treatment

…High Obesity 35.0–39.9 II Very high Extreme obesity ≥40 III Extremely high BMI is useful for screening and population level risk estimation…

Acute Limb Ischaemia: Recognition and Urgent Management

…medicine Emergency medicine Definition and pathophysiology Acute limb ischaemia (ALI) is an abrupt reduction in arterial perfusion of an upper or lower limb that causes…

Anthropometric measurements

…25 and 35. Body mass index For people of South Asian, Chinese and Japanese origin, lower thresholds apply: overweight from a BMI of 23 and…

Blood pressure

…least two occasions, and preferably confirmation by home measurement or 24 hour recording — the thresholds for which are lower than for office measurement. Classification of…

Hyperkalaemia: quick reference for emergency treatment

…Record a 12 lead ECG and start cardiac monitoring at a plasma potassium above 6.0 mmol/L, and at lower values if the rise…

Hypertensive crisis: quick reference for acute blood pressure lowering

…Ask specifically about: Neurological symptoms: confusion, visual loss, focal neurological signs, seizures, severe or sudden headache. Chest pain, back pain, dyspnoea, orthopnoea and new sweating…

Lung function and respiration

…height and ethnicity — not against absolute figures. Since 2022 the z score with a lower limit of normal at z = −1.64 (the fifth…

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