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Liver parameters

…in people under 40, alpha 1 antitrypsin, TSH and coeliac serology , together with ultrasound of the liver and biliary tract . Go through the medication and…

Opioid therapy in severe pain

…biliary tract disease. There is no contraindication to analgesia in the acute abdomen . The notion that an opioid masks the diagnosis has been disproved — withholding…

Inclisiran and Emerging Lipid-Lowering Agents

…receiving statins, inclisiran produced a further reduction in LDL C of approximately 50%. The effect was consistent in patients with and without diabetes. A pooled…

Amiodarone: Loading, Maintenance Dosing and Monitoring Schedule

…metabolite accumulate extensively in various tissues, including the liver, lung, fat, and skin, with myocardial concentrations reaching 10 to 50 times those found in plasma…

Preeclampsia and Hypertensive Pregnancy Disorders as Future Cardiovascular Risk

…is the occurrence of new onset seizures or coma in a pregnant woman with preeclampsia. HELLP syndrome—haemolysis, elevated liver enzymes or transaminases, and thrombocytopenia…

Sepsis and septic shock: quick reference for the first hour

…output, respiration, chest findings, MAP and the response to every intervention Within 60 min Contact intensive care in shock, rapidly progressive organ dysfunction, respiratory failure…

🟠 ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) Bleeding Risk Score

…et al. A new risk scheme to predict warfarin associated hemorrhage: the ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) study. J Am Coll Cardiol…

Bempedoic Acid: Evidence and Clinical Use

…is a prodrug activated predominantly in the liver by very long chain acyl CoA synthetase 1. This activating enzyme is not expressed in skeletal muscle…

Dietary Patterns and Cardiovascular Outcomes

…in a single intermediate marker such as cholesterol. Dietary composition may influence blood pressure, glucose–insulin homeostasis, lipids and apolipoproteins, endothelial function, systemic inflammation, liver…

Ezetimibe: Place in Therapy and Expected LDL-C Reduction

…Definition and pharmacological basis Ezetimibe is a non statin lipid lowering agent that inhibits the Niemann–Pick C1 like 1 (NPC1L1) transporter in the intestine…

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