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Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

…Endothelial and smooth muscle cells normally regulate vascular tone, preserve an antithrombotic surface, and control the adhesion and migration of inflammatory cells. Dyslipidaemia, cigarette smoking…

ST-Elevation Myocardial Infarction: Diagnosis and Electrocardiographic Criteria

…as no reflow, structural and functional impairments sustain vascular obstruction. Endothelial dysfunction triggers leukocyte and platelet activation, while thrombotic debris may worsen the obstruction. Furthermore…

ST-Segment Elevation Myocardial Infarction: Diagnosis and ECG Criteria

…also by the vulnerability of the myocardium and coronary microcirculation. Endothelial dysfunction promotes leukocyte and platelet activation and interaction. Thrombotic debris may worsen microvascular obstruction…

ST-Elevation Myocardial Infarction Complicated by Cardiogenic Shock

…after epicardial flow is restored. Microvascular obstruction may persist despite successful PCI because of endothelial dysfunction, leukocyte and platelet interaction, distal thrombotic debris, cardiomyocyte swelling…

Post-Infarction Pericarditis and Dressler Syndrome

…At pathological examination, Dressler syndrome is generally characterized by localized fibrinous pericarditis containing polymorphonuclear leukocytes. Important distinction from subacute cardiac rupture A post AMI pericardial…

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