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Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…years later in females. Untreated HoFH is associated with extensive premature and progressive ASCVD; CAD and aortic stenosis may occur before the age of 20…

Alcohol withdrawal and delirium tremens: quick reference

…90 percent of withdrawal seizures occur within 48 hours. Seizures later than this, focal seizures or status epilepticus should raise strong suspicion of another or…

Corticosteroids: quick reference for dose equivalents and stress dosing

Endokrinologi & metabolism Farmakologi & dosering Lathundar Two situations are often confused: replacement therapy in adrenal insufficiency (which must be increased under stress) and pharmacological anti inflammatory…

Drug-Eluting Coronary Stents: Evolution, Evidence and Stent Choice

…and lower thrombogenicity. Stent thrombosis Early metallic stents reduced acute closure but introduced the risk of thrombosis related to the intravascular foreign body. First generation…

Opioid therapy in severe pain

…morphine Morphine has an active renally excreted metabolite that causes late sedation and respiratory depression Marked liver failure A reduced dose of all of them…

In-Stent Restenosis: Mechanisms and Treatment

…risk of restenosis after metallic stent implantation is increased by: Small reference vessel size A small post procedural luminal diameter A high degree of residual…

Factors that modify the natural course in acute myocardial infarction (AMI)

…case of a partial occlusion. Coronary artery anatomy There is individual variation in the coronary artery anatomy. These details will be discussed in later chapters…

Liver parameters

…The tests that reflect the synthetic function of the liver are the prothrombin time (INR) , the albumin and the bilirubin — and they become abnormal late…

Fourth Universal Definition of Myocardial Infarction: Types 1–5

…of myocardial infarction (MI) has evolved significantly over the past century. Initial post mortem observations in the late 19th century first linked thrombotic occlusion of…

Post-Infarction Pericarditis and Dressler Syndrome

…is usually transient. Late post acute myocardial infarction pericarditis , traditionally termed Dressler syndrome , which is a manifestation of post cardiac injury syndrome (PCIS). PCIS is…

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