…is the most common presenting complaint. The pain is deep and visceral, frequently described as heavy, squeezing, and crushing, though it may occasionally be reported…

…than to transmurality. Clinical Presentation and Symptoms Typical presentation Pain is the most frequent presenting symptom. It is generally deep and visceral, often described as…

…congestion, systemic venous hypertension, and peripheral interstitial edema. These abnormalities produce breathlessness, orthopnea, weight gain, peripheral edema, early satiety, abdominal distension and, in some patients…

…metalloproteinases (MMPs) degrade the interstitial collagen of the cap, leading to structural failure. Rupture exposes highly thrombogenic subendothelial matrix components, notably tissue factor and collagen…

…producing abundant extracellular matrix (ECM) components, primarily interstitial collagen types I and III, elastin, and proteoglycans [6] . This matrix forms a fibrous cap that sequesters…

…and the arrhythmia itself. This remodeling manifests as interstitial fibrosis, atrial dilation, and endocardial denudation, which collectively promote local inflammation and create a highly prothrombotic…

…PCI because of endothelial dysfunction, leukocyte and platelet interaction, distal thrombotic debris, cardiomyocyte swelling, interstitial edema, and inflammatory extravascular compression. This impaired tissue perfusion can…

…sample and send a venous plasma glucose, but do not delay treatment of a neurologically compromised patient. Continuous glucose monitoring reflects interstitial glucose and lags…

…of its high blood flow and the concentration of filtered substances along the nephron as water is reabsorbed. Nephrotoxic injury may involve the tubules, interstitium…