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Diuretic Strategy and Decongestion in Heart Failure

…of the heart to provide blood flow appropriate to tissue requirements unless filling pressures are elevated. Consequently, congestion may occur across the full range of…

The Fourth Universal Definition of Myocardial Infarction: Types 1–5

…laboratory medicine Myocardial ischemia and infarction Definition and pathophysiology Myocardial infarction (MI) is a clinical diagnosis that integrates myocardial injury, evidence of acute myocardial ischaemia…

Myocardial Injury Versus Infarction: Interpreting Troponin Elevation

…ischaemic ECG changes. The distinction between myocardial injury and type 2 infarction is particularly important. Type 2 infarction requires clinical evidence of ischaemia; an elevated…

STEMI: Primary PCI and System-of-Care Time Targets

…of initial STEMI management. The principal acute complications fall into two broad categories: Electrical complications , particularly ventricular arrhythmias. Mechanical or pump failure complications , including heart…

Complications of Coronary Angiography and Vascular Access Management

…and procedural risk factors The risk of adverse events is increased by: advanced age; diabetes mellitus; chronic kidney disease or renal failure; congestive heart failure…

Immediate Management of Type A and Type B Aortic Dissection

…disruption, rupture and compromise of branch vessels. Type A disease may cause cardiac tamponade, severe acute aortic regurgitation, coronary malperfusion, myocardial ischaemia, heart failure, shock…

Fourth Universal Definition of Myocardial Infarction: Types 1–5

…by the World Health Organization in the mid 20th century, relying primarily on electrocardiographic criteria for epidemiological purposes. With the advent of highly sensitive cardiac…

The 3-phase model of sudden cardiac arrest

…energy source in all cells]). The heart consumes approximately 30 kilograms of ATP per day (Neubauer et al), which is about 100 times its weight…

Contrast-Associated Acute Kidney Injury: Risk Assessment and Prevention

…exposures may contribute to tubular injury, making attribution to contrast alone difficult. In patients with normal renal function, the occurrence of contrast induced AKI is…

Cardiovascular effects of COVID-19 (Coronavirus Disease 2019)

…al, JAMA Cardiology (2020). Guo et al reported that 27.8% (52 of 187 patients) had myocardial injury, defined as elevated troponin T levels (TnT)…

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