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🟠 Aspirin (Acetylsalicylic acid)

Indications Acute myocardial infarction. Unstable coronary artery disease. Stable angina pectoris. Secondary prophylaxis to prevent recurrence of cerebrovascular diseases, such as: Transient ischemic attacks (TIA…

Cardiovascular Risk in Inflammatory and Autoimmune Disease

…with inflammatory rheumatic disease have a higher cardiovascular risk than the general population. This excess risk has been documented across a broad range of conditions…

Colchicine and Anti-inflammatory Therapy in Coronary Disease

…Mechanisms of action Colchicine Colchicine appears to exert several anti inflammatory effects relevant to coronary disease: Reduction of inflammasome activation. Inhibition of interleukin 1β…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

…source of an acute myocardial infarction during long term follow up. Moreover, several potentially high risk plaques may coexist within one coronary tree, and inflammatory…

Cardiac arrest during sepsis

…systemic inflammatory response syndrome (SIRS), disseminated intravascular coagulation (DIC), and hypoperfusion manifesting as hypotension. The high mortality associated with sepsis underscores the critical importance of…

Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

Introduction to Coronary Atherosclerosis, Plaques, Atherothrombosis Coronary atherosclerosis is a chronic, progressive, and highly dynamic inflammatory disease of the arterial wall. It is characterized by…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…progressive, and highly complex lipid driven inflammatory disease of the arterial intima that serves as the fundamental pathophysiological substrate for acute coronary syndromes (ACS), including…

Corticosteroids: quick reference for dose equivalents and stress dosing

…36–54 hours The equivalences apply to the anti inflammatory effect. They say nothing about the mineralocorticoid effect or about suppression of the HPA axis…

Isoprenaline and Dopamine Infusions for Bradycardia

…involvement, and atrioventricular block (AVB) may indicate septal involvement in the inflammatory process. A broad spectrum of pharmacologic agents can induce bradycardia or conduction disorders…

Cardiac arrest in hyperthermia and malignant hyperthermia

…to the Systemic Inflammatory Response Syndrome (SIRS). Body temperatures surpassing 40°C (104°F) are potentially hazardous and may precipitate cardiac arrest. The classification of hyperthermia is…

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