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🟠 Aspirin (Acetylsalicylic acid)

…by: Acetylsalicylic acid (aspirin). Other non steroidal anti inflammatory drugs (NSAIDs). Other contraindications: Hemophilia. Thrombocytopenia. Active gastric or duodenal ulcers. Liver cirrhosis. Severe heart failure…

Bempedoic Acid: Evidence and Clinical Use

…despite maximally tolerated therapy. It is a prodrug activated predominantly in the liver by very long chain acyl CoA synthetase 1. This activating enzyme is…

Metabolic Syndrome: Definition and Clinical Significance

…inflammatory component and may progress to cirrhosis and end stage liver disease. Metabolic dysfunction associated fatty liver disease is also independently related to cardiovascular disease…

Preeclampsia and Hypertensive Pregnancy Disorders as Future Cardiovascular Risk

…woman with preeclampsia. HELLP syndrome—haemolysis, elevated liver enzymes or transaminases, and thrombocytopenia—is generally regarded as a severe preeclamptic phenotype or variant. Pathophysiology The…

Incretins in Cardiometabolic Medicine: Leveraging GLP-1, GIP, and Glucagon Receptor Agonism for Cardiovascular Risk Reduction

…the reductions in hard cardiovascular outcomes (MI, stroke) and metabolic liver disease involve significant weight independent pathways. 15 Metabolic Reprogramming and Vascular Health GLP 1…

Cardiovascular Risk in Inflammatory and Autoimmune Disease

…cardiovascular risk. Dyslipidaemia may be difficult to interpret during active disease: inflammatory cytokines can lower LDL and HDL concentrations while increasing the atherogenic index, a…

Colchicine and Anti-inflammatory Therapy in Coronary Disease

…Clinical application and patient populations The evidence for anti inflammatory treatment in coronary disease has principally involved two populations: Patients recently recovering from myocardial infarction…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

Cardiology Myocardial ischemia and infarction Definition and pathophysiology Atherosclerosis is a chronic, inflammatory disease of the arterial wall in which lipid accumulation, vascular cell dysfunction…

Cardiac arrest during sepsis

CPR Sepsis induced cardiac arrest Sepsis is a life threatening condition characterized by systemic inflammatory response syndrome (SIRS), disseminated intravascular coagulation (DIC), and hypoperfusion manifesting…

Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

…a chronic, progressive, and highly dynamic inflammatory disease of the arterial wall. It is characterized by the subendothelial accumulation of apolipoprotein B containing lipoproteins, macrophage…

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