11 träffar

DrugACE inhibitor for intravenous use
Enalaprilat

…The active metabolite of enalapril, given directly intravenously. Rarely used in hypertensive crisis: onset is slow, duration 8–24 hours, and the effect varies widely…

DrugSelective dopamine-1 receptor agonist
Fenoldopam

…alpha or beta effects, with onset within minutes and duration under one hour — theoretically attractive in hypertensive crisis with renal involvement, but without documented hard…

DrugDirect-acting arteriolar vasodilator
Hydralazine

…making the drug unsuitable as first-line treatment in hypertensive crisis — but useful in pre-eclampsia and as afterload relief in combination with a nitrate…

DrugNon-selective α-adrenergic blocker
Phentolamine

…selective alpha-blocker with onset within minutes and duration under half an hour. A niche drug: catecholamine-induced hypertensive crisis — phaeochromocytoma, cocaine and amphetamine intoxication…

DrugKombinerad α₁- och β-blockerare
🇸🇪 Labetalol

Trandate Kombinerad α₁- och β-blockerare Arbetshästen vid hypertensiv kris i Sverige. Den kombinerade alfa- och betablockaden sänker trycket utan reflextakykardi, vilket gör preparatet användbart…

DrugDihydropyridin-kalciumantagonist
🇸🇪 Nicardipine

…men mer förlåtande. Ger relativt mer venodilatation än arteriolär dilatation jämfört med nitroprussid, och är ett förstahandsalternativ vid hypertensiv kris med graviditet eller cerebrovaskulär sjukdom.

DrugKvävemonoxiddonator (organiskt nitrat)
🇸🇪 Nitroglycerin

…både vener och artärer — vendilatationen dominerar vid låga doser och sänker preload, artärdilatationen tillkommer vid högre doser. Förstahandsval vid hypertensiv kris med lungödem eller myokardischemi.

DrugLong-acting dihydropyridine calcium channel blocker
Amlodipine

Norvasc Amlodipin Sandoz Amlodipine Teva Long-acting dihydropyridine calcium channel blocker A cornerstone drug for hypertension and stable angina, and the easiest calcium channel blocker…

DrugThiazide diuretic
Bendroflumethiazide

Salures Bendroflumetiazid Evolan Thiazide diuretic Inhibits the Na⁺/Cl⁻ cotransporter in the distal tubule and is the most commonly used thiazide diuretic for hypertension. The…

DrugVascular-selective dihydropyridine calcium channel blocker
Felodipine

…Logimax Vascular-selective dihydropyridine calcium channel blocker A highly vascular-selective dihydropyridine given as a modified-release tablet once daily for hypertension and stable angina…

DrugAngiotensin II receptor blocker (ARB)
Candesartan

…when an ACE inhibitor must be switched due to cough. The target dose in heart failure is 32 mg — four times the usual hypertension dose.